The measures are some of the toughest yet but Hungary has rejected them as unacceptable.
Burnley's latest accounts show the club would have to repay a "significant proportion" of a £65m loan at the end of the season if relegated from the Premier League.
Researchers at the Terasaki Institute have now shown that silk scaffolds loaded with stem cells can help tendons regenerate more effectively. New Atlas reports: For the new study, the Terasaki researchers developed their own scaffold that could support the tendon while it healed. This scaffold was made of silk fibroin paired with a hydrogel known as GelMA -- the former gave the scaffold strength and stretchability, while the latter is biocompatible and encourages cells to attach and grow. After experimenting to get the right ratios of ingredients, the team fabricated nanofiber sheets of their silk fibroin and GelMA (SG) material. Then the sheets are seeded with mesenchymal stem cells (MSCs), which can not only differentiate into several cell types, but also aid regeneration by producing signaling molecules that summon immune cells to the area and encourage new blood vessels to form. The team tested these stem-cell-loaded SG sheets in rats with injuries to their Achilles tendons. Compared to other scaffolds loaded with stem cells, those made of SG healed the tendons the fastest, while also forming densely packed tendon fibers, reducing injury sites, and remodeling the muscle components. "The synergistic effects of GelMA's capacity for supporting regenerative tissue formation and the structural advantages of silk fibroin make our composite material well suited for tendon repair," said HanJun Kim, lead researcher on the study. The team hopes that with further work, the stem-cell-loaded scaffolds could eventually lead to new therapies for tendon injuries. The research has been published in the journal Small.
Read more of this story at Slashdot.
Warrington Wolves winger Josh Charnley says he was "shocked" to be sent a death threat on social media.
The rising cost of living dominates the final day of campaigning as parties pitch to voters.
The over-budget project was meant to open in December 2018 but will now begin running on 24 May.
The Labour leader says he has had no further contact with the Durham force after claims he broke rules.
Bidding for the shirt Diego Maradona wore scoring the "Hand of God" goal has already reached £4m.
Liverpool manager Jurgen Klopp praises his side for surviving a first-half scare against Villarreal to win 3-2 and reach the Champions League final.
A man suspected of assaulting comedian Dave Chappelle on stage had a dummy gun and knife, police say.